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Powerpoint Slides tags by : bone marrow
 

Dose-rate effects of protons on in vivo activation of nuclear factor-kappa B and cytokines in mouse bone marrow cells.
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The objective of this study was to determine the kinetics of nuclear factor-kappa B (NF-kappaB) activation and cytokine expression in bone marrow (BM) cells of exposed mice as a function of the dose

MRI bone marrow findings in 63 patients with type I Gaucher disease.
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PURPOSE To determine whether MR bone marrow findings in Gaucher patients may help to identify patients at high risk of developing severe Gaucher bone complications exemplified by avascular necrosis (

Consensus statement from European experts on the diagnosis management and treatment of multiple myeloma from standard therapy to novel approaches.
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Treatment for multiple myeloma (MM) has changed beyond recognition over the past two decades. During the early 1980s MM inevitably resulted in a slow progressive decline in quality of life until deat

Induction of neuro-protective/regenerative genes in stem cells infiltrating post-ischemic brain tissue.
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ABSTRACT BACKGROUND- Although the therapeutic potential of bone marrow-derived stromal stem cells (BMSC) has been demonstrated in different experimental models of ischemic stroke it remains unclear h

Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum.
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BACKGROUND The Plasmodium falciparum parasite is transmitted in its sexual gametocyte stage from man to mosquito and as asexual sporozoites from mosquito to man. Developing gametocytes sequester pref

Specific "intra-allele" and "intra-broad antigen" human leukocyte antigen alloantibodies in kidney graft transplantation.
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Human leukocyte antigen (HLA) antibodies are epitope specific and not antigen specific. This work presents a case of intra-allele (IA) sensitization. A 40-year-old-man underwent transplantion with id

A bone to pick with compulsive behavior.
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Mice with mutations in the Hoxb8 gene exhibit compulsive grooming behavior. Chen et al. (2010) now report that this behavior stems from Hoxb8 deficiency in microglia a type of immune cell in the brai

Phase I study of temozolomide and laromustine (VNP40101M) in patients with relapsed or refractory leukemia.
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PURPOSE Although alkylators are known to be effective against some myeloid leukemias resistance is often mediated via O6-alkylguanine-DNA alkyltransferase (AGT). Temozolomides inhibition of AGT may s

Epigenetic molecular genetics in Multiple Myeloma
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Abstract Multiple Myeloma (MM) is a malignant hematological disease that is characterized by clonal expansion of malignant plasma cells/plasmablasts in the bone marrow (BM). MM is a very heterogenou

Osteonecrosis of hip and knee in patients with severe acute respiratory syndrome treated with steroids.
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PURPOSE: To evaluate whether there is a relationship between steroid treatment and risk for osteonecrosis of the hip and knee in patients with severe acute respiratory syndrome (SARS). MATERIALS AND
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