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Role of heme oxygenase in inflammation insulin-signalling diabetes and obesity.
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Diabetes and obesity are chronic conditions associated with elevated oxidative/inflammatory activities with a continuum of tissue insults leading to more severe cardiometabolic and renal complication

Release of inflammatory mediators by human adipose tissue is enhanced in obesity and primarily by the nonfat cells a review.
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This paper considers the role of putative adipokines that might be involved in the enhanced inflammatory response of human adipose tissue seen in obesity. Inflammatory adipokines IL-6 IL-10 ACE TGFbe

Antioxidant effect of Triticum aestivium (wheat grass) in high-fat diet-induced oxidative stress in rabbits.
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Wheat grass is used as a general health tonic and is reported to be effective against several medical disorders although detailed literature is not available. Besides drug therapy a number of medicin

The effectiveness of packed therapy with three drugs in Helicobacter pylori eradication in Japan.
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Primary Helicobacter pylori eradication rate using triple therapy (a proton pump inhibitor PPI + amoxicillin AMPC + clarithromycin CAM over 7 days) is showing a declining trend. In this study we repo

Genotypes and haplotypes of the estrogen receptor genes but not the retinoblastoma-interacting zinc finger protein 1 gene are associated with osteoporosis.
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Osteoporosis is a common age-related disease with a strong genetic influence. Polymorphisms of ESR1 have consistently been shown to be associated with bone mineral density (BMD) and fracture however

Prediction of protein-ligand binding affinity by free energy simulations assumptions pitfalls and expectations.
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Many limitations of current computer-aided drug design arise from the difficulty of reliably predicting the binding affinity of a small molecule to a biological target. There is thus a strong interes

Dose-rate effects of protons on in vivo activation of nuclear factor-kappa B and cytokines in mouse bone marrow cells.
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The objective of this study was to determine the kinetics of nuclear factor-kappa B (NF-kappaB) activation and cytokine expression in bone marrow (BM) cells of exposed mice as a function of the dose

Contribution of rheumatoid arthritis disease activity and disability to rheumatoid cachexia.
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This cross-sectional study was done to show how nutritional indices influence each other and the contributions made by inflammation to the development of rheumatoid cachexia. We studied 295 female pa

Anemia of chronic disorder - pathogenesis clinical presentation and treatment.
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After iron deficiency anemia the anemia of chronic disorder is the second most frequent anemia and in hospitalized patients and/or patients suffering from chronic disease especially infection cancer

Methane storage in porous metal-organic frameworks current records and future perspectives.
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Porous metal-organic frameworks (MOFs) are a novel family of physisorptive materials exhibiting great potential for methane storage applications. Several MOF compounds have been reported to exhibit h
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