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Powerpoint Slides tags by : apoptosis
 

Tumor cell behaviour modulation by mesenchymal stromal cells.
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BACKGROUND Human mesenchymal stromal cells (MSC) hold a promise for future cell-based therapies due to their immunomodulatory properties and/or secretory activity. Nevertheless non-neoplastic tumor c

TNF and IL-10 are major factors in modulation of the phagocytic cell environment in lung and lymph node in tuberculosis a next-generation two-compartmental model.
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Tuberculosis (TB) is one of the earliest recorded human diseases and still one of the deadliest worldwide. Its causative agent is the bacteria Mycobacterium tuberculosis (Mtb). Cytokine-mediated macr

Sulforaphane induces DNA single strand breaks in cultured human cells.
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Sulforaphane (SFR) an isothiocyanate from cruciferous vegetables possesses growth-inhibiting and apoptosis-inducing activities in cancer cell lines. Recently SFR has been shown to promote the mitocho

Immunohistochemical evaluation of macrophage activity and its relationship with apoptotic cell death in the polar forms of leprosy.
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The objective of the present study was to investigate the correlation between macrophage activity and apoptosis in the polar forms of leprosy because the immunopathological phenomena involved in thes

Freewheel training decreases pro- and increases anti-inflammatory cytokine expression in mouse intestinal lymphocytes.
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Intestinal inflammation and inflammatory bowel diseases (IBD) may occur due to imbalances in pro- and anti-inflammatory cytokines. Long-term exercise reduces the risk for IBD. The purpose of this stu

RXRgamma and PPARgamma ligands in combination to inhibit proliferation and invasiveness in colon cancer cells.
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Nuclear retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs are potential candidates as drug target for cancer prevention and treatment. We investigated if the rexinoid

Synthesis and in vitro evaluation of novel 124-triazine derivatives as neuroprotective agents.
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The role of novel triazine derivatives against oxidative stress exerted by hydrogen peroxide on differentiated rat pheochromocytoma (PC12) cell line was examined and a consistent protection from H(2)

Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization.
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NMDA receptor-dependent synaptic modifications such as long-term potentiation (LTP) and long-term depression (LTD) are essential for brain development and function. LTD occurs mainly by the removal o

AKAP121 downregulation impairs protective cAMP signals promotes mitochondrial dysfunction and increases oxidative stress.
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AIMS The aim of the present study was to determine the function and the role of the scaffold protein AKAP121 tethering cAMP dependent protein kinase A to the outer wall of mitochondria in neonatal ve

Apoptosis in Polycystic Kidney Disease
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