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PARANEOPLASTIC OPTIC NEURITIS IN A UNKNOWN SMALL CELL LUNG CARCINOMA DEFINED BY CRMP-5-IgG
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The case of a 64-year-old patient with bilateral, progressive and painless diminution of visual acuity is presented. Ophthalmologic evaluation revealed optic neuritis and vitreous cells in both eyes,

Interstitial lung disease associated to erlotinib treatment a case report.
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ABSTRACT INTRODUCTION Few cases of pulmonary toxicity related to epidermal growth factor receptor-targeted agents have been described. CASE PRESENTATION We report a case of a 63-year-old white male w

(Pre-)clinical pharmacology and activity of pazopanib a novel multikinase angiogenesis inhibitor.
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Pazopanib is a recently approved novel tyrosine kinase inhibitor specifically designed to impair angiogenesis by abrogating vascular endothelial growth factor receptor 2 (VEGFR-2) to exert its functi

Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.
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