Abstract : Wheat grass is used as a general health tonic and is reported to be effective against several medic
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Abstract : Wheat grass is used as a general health tonic and is reported to be effective against several medical disorders although detailed literature is not available. Besides drug therapy a number of medicinal plants are effective in treating hyperlipidemia. This study examined the effects of wheat grass on high-fat diet-induced hyperlipidemia in rabbits. Thirty rabbits were divided into 3 groups of 10 rabbits each group I receiving a control diet group II a high-fat diet and group III a high-fat diet together with wheat grass over a period of 10 weeks. Fasting serum samples from the animals were analyzed for total cholesterol (TC) high-density lipoprotein cholesterol (HDL-C) malondialdehyde (MDA) reduced glutathione (GSH) and vitamin C and the results were compared. The high-fat diet resulted in hyperlipidemia and an increase in oxidative stress indicated by a significant rise in MDA levels whereas antioxidant levels of GSH and vitamin C were significantly reduced. Wheat grass supplementation with a high-fat diet resulted in improved lipid levels (decreased total cholesterol and increased HDL-C) together with significantly reduced MDA levels and increased GSH and vitamin C levels. These results indicate the beneficial role of wheat grass in ameliorating hyperlipidemia and the associated oxidative stress.Copyright 2010 Prous Science S.A.U. or its licensors. All rights reserved.PMID 20508870 PubMed - indexed for MEDLINEMeSH Terms SubstancesMeSH TermsAnimalsAntioxidants/pharmacology*Ascorbic Acid/metabolismDietary Fats/toxicityFemaleGlutathione/drug effectsGlutathione/metabolismHyperlipidemias/drug therapy*Hyperlipidemias/physiopathologyMaleMalondialdehyde/metabolismOxidative Stress/drug effects*Phytotherapy/methodsPlant Preparations/pharmacologyRabbitsTriticum/chemistry*SubstancesAntioxidantsDietary FatsPlant PreparationsAscorbic AcidMalondialdehydeGlutathioneLinkOut - more resourcesFull Text SourcesProus ScienceMedicalAntioxidants - MedlinePlus Health InformationMolecular Biology DatabasesSODIUM ASCORBATE - HSDBMALONALDEHYDE - HSDBASCORBIC ACID - HSDB Supplemental Content Related citations Randomized controlled trial of antioxidant vitamins and cardioprotective diet on hyperlipidemia oxidative stress and development of experimental atherosclerosis the diet and antioxidant trial on atherosclerosis (DATA). Cardiovasc Drugs Ther. 1995 Randomized controlled trial of antioxidant vitamins and cardioprotective diet on hyperlipidemia oxidative stress and development of experimental atherosclerosis the diet and antioxidant trial on atherosclerosis (DATA).Singh RB Niaz AM Ghosh S Agarwal P Ahmad S Begum R Onouchi Z Kummerow FA. Cardiovasc Drugs Ther. 1995 Dec 9(6)763-71. Susceptibility to hepatic oxidative stress in rabbits fed different animal and plant fats. J Am Coll Nutr. 1996 Susceptibility to hepatic oxidative stress in rabbits fed different animal and plant fats.Slim RM Toborek M Watkins BA Boissonneault GA Hennig B. J Am Coll Nutr. 1996 Jun 15(3)289-94. Regression of hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Atherosclerosis. 2008 Regression of hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed.Prasad K. Atherosclerosis. 2008 Mar 197(1)34-42. Epub 2007 Sep 29. Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed. Atherosclerosis. 2005 Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed.Prasad K. Atherosclerosis. 2005 Apr 179(2)269-75. Epub 2005 Jan 26. Effects of flaxseed oil on serum lipids and atherosclerosis in hypercholesterolemic rabbits. J Cardiovasc Pharmacol Ther. 2003 Effects of flaxseed oil on serum lipids and atherosclerosis in hypercholesterolemic rabbits.Lee P Prasad K. J Cardiovasc Pharmacol Ther. 2003 Sep 8(3)227-35. See reviews... See all... All links from this record Related Citations Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant with the “linked from” citation displayed first. Compound (MeSH Keyword) PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles. Substance (MeSH Keyword) PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles. Recent activity Clear Turn Off Turn On Antioxidant effect of Triticum aestivium (wheat grass) in high-fat diet-induced ... Antioxidant effect of Triticum aestivium (wheat grass) in high-fat diet-induced oxidative stress in rabbits.Methods Find Exp Clin Pharmacol. 2010 May 32(4)233-5. PubMed Your browsing activity is empty. Activity recording is turned off. Turn recording back on See more... 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