Abstract : Cynomolgus monkeys have been maintained in indoor facilities as closed colony monkeys in Tsukuba Pr
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Abstract : Cynomolgus monkeys have been maintained in indoor facilities as closed colony monkeys in Tsukuba Primate Research Center in Japan since 1978. Several microorganisms including bacteria parasites and viruses were eliminated from the cynomolgus monkeys in this colony of TPRC. Various kinds of viruses (B virus measles virus simian varicella virus simian immunodeficiency virus simian T cell leukemia virus simian D type retrovirus simian cytomegalovirus simian Epstein-Barr virus and simian foamy virus) bacteria (Shigella Salmonella and Mycobacteria spp.) and intestinal helminth were chosen as target microorganisms to establish a specific pathogen-free (SPF) colony. Except for a few pathogens (simian D type retrovirus simian Epstein-Barr virus and simian foamy virus) selected pathogens were completely eliminated from all monkeys in TPRC. In this review the history of establishment of SPF cynomolgus monkey colonies in Japan is described.Copyright (c) 2009 Elsevier Ltd. All rights reserved.PMID 20510748 PubMed - indexed for MEDLINEPublication Types MeSH TermsPublication Types Research Support Non-U.S. GovtReviewMeSH TermsAnimalsBreedingJapanMacaca fascicularis*/microbiologyMacaca fascicularis*/parasitologyMacaca fascicularis*/virologyModels Animal*Specific Pathogen-Free Organisms*LinkOut - more resourcesFull Text SourcesElsevier ScienceEBSCOOhioLINK Electronic Journal CenterSwets Information Services Supplemental Content Related citations Survey of captive cynomolgus macaque colonies for SRV/D infection using polymerase chain reaction assays. Comp Med. 2005 Survey of captive cynomolgus macaque colonies for SRV/D infection using polymerase chain reaction assays.Hara M Kikuchi T Ono F Takano J Ageyama N Fujimoto K Terao K Baba T Mukai R. Comp Med. 2005 Apr 55(2)145-9. Review Specific pathogen-free macaques definition history and current production. ILAR J. 2008 Review Specific pathogen-free macaques definition history and current production.Morton WR Agy MB Capuano SV Grant RF. ILAR J. 2008 49(2)137-44. Establishing specific retrovirus-free breeding colonies of macaques an approach to primary screening and surveillance. Lab Anim Sci. 1994 Establishing specific retrovirus-free breeding colonies of macaques an approach to primary screening and surveillance.Lerche NW Yee JL Jennings MB. Lab Anim Sci. 1994 Jun 44(3)217-21. Isolation and characterization of a new simian retrovirus type D subtype from monkeys at the Tsukuba Primate Center Japan. Microbes Infect. 2005 Isolation and characterization of a new simian retrovirus type D subtype from monkeys at the Tsukuba Primate Center Japan.Hara M Sata T Kikuchi T Nakajima N Uda A Fujimoto K Baba T Mukai R. Microbes Infect. 2005 Jan 7(1)126-31. Epub 2004 Dec 10. Review Simian and feline immunodeficiency viruses animal lentivirus models for evaluation of AIDS vaccines and antiviral agents. Antiviral Res. 1991 Review Simian and feline immunodeficiency viruses animal lentivirus models for evaluation of AIDS vaccines and antiviral agents.Gardner MB. Antiviral Res. 1991 May 15(4)267-86. See reviews... See all... Recent activity Clear Turn Off Turn On Establishment of specific pathogen-free macaque colonies in Tsukuba Primate Rese... Establishment of specific pathogen-free macaque colonies in Tsukuba Primate Research Center of Japan for AIDS research.Vaccine. 2010 May 26 28 Suppl 2B75-7. PubMed Your browsing activity is empty. Activity recording is turned off. Turn recording back on See more... You are here NCBI gt Literature gt PubMed Write to the Help Desk Simple NCBI Directory Getting Started NCBI Education NCBI Help Manual NCBI Handbook Training amp Tutorials Resources Chemicals amp BioassaysData amp SoftwareDNA amp RNADomains amp StructuresGenes amp ExpressionGenetics amp MedicineGenomes amp MapsHomologyLiteratureProteinsSequence AnalysisTaxonomyTraining amp TutorialsVariation Popular PubMed Nucleotide BLAST PubMed Central Gene Bookshelf Protein OMIM Genome SNP Structure Featured GenBank Reference Sequences Map Viewer Genome Projects Human Genome Mouse Genome Influenza Virus Primer-BLAST Sequence Read Archive NCBI Information About NCBI Research at NCBI NCBI Newsletter NCBI FTP Site NCBI on Facebook NCBI on Twitter NCBI on YouTube NIH DHHS USA.gov Copyright | Disclaimer | Privacy | Accessibility | Contact National Center for Biotechnology Information U.S. National Library of Medicine 8600 Rockville Pike Bethesda MD 20894 USA
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