Abstract : The statistical R.O.C. analysis method is commonly used to evaluate the efficacy of a single diagno
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Abstract : The statistical R.O.C. analysis method is commonly used to evaluate the efficacy of a single diagnostic modality. The implementation of new modalities, commonly complementary, makes it necessary to evaluate the contribution obtained by several modalities at the same time. From the statistical point of view, it is necessary to build a R.O.C. curve taking into account the overall diagnostic information content, i.e. a R.O.C. curve in an N-dimensional space. The present work’s aim is to set up a procedure that, using a generalized form of the discriminant analysis, can build a R.O.C. curve based on a new virtual mono-dimensional variable whose values from the discriminant function are obtained. The proposed method was tested in several experimental situations, such as a mammary Magnetic Resonance study combined with scinti-mammography and traditional mammography studies. A short description of a computerized procedure, written in Visual Basic™ Pro ( v.6.0 ), which automatically performs the statistical analysis and the R.O.C. curves plot is given as well.- Slides
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