Abstract : Liver transplantation has been remarkably effective in the treatment in patients with end-stage liv
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Abstract : Liver transplantation has been remarkably effective in the treatment in patients with end-stage liver disease. However disparity between solid-organ supply and increased demand is the greatest limitation resulting in longer waiting times and increase in mortality of transplant recipients. This situation creates the need to seek alternatives to orthotopic liver transplantation.Hepatocyte transplantation or liver cell transplantation has been proposed as the best method to support patients. The procedure consists of transplanting individual cells to a recipient organ in sufficient quantity to survive and restore the function. The capacity of hepatic regeneration is the biological basis of hepatocyte transplantation. This therapeutic option is an experimental procedure in some patients with inborn errors of metabolism fulminant hepatic failure and acute and chronic liver failure as a bridge to orthotopic liver transplantation. In the Hospital La Fe of Valencia we performed the first hepatocyte transplantation in Spain creating a new research work on transplant program.Copyright 2009 AEC. Published by Elsevier Espana. All rights reserved.PMID 20510402 PubMed - indexed for MEDLINEFree ArticlePublication Types MeSH TermsPublication Types English MeSH TermsHepatocytes/transplantation*HumansLiver Diseases/surgery*LinkOut - more resourcesFull Text SourcesEdiciones Doyma S.L.Elsevier ScienceMedicalLiver Diseases - MedlinePlus Health Information Supplemental Content Related citations Hepatocellular transplantation in acute hepatic failure and targeting genetic markers to hepatic cells. Hum Gene Ther. 1991 Hepatocellular transplantation in acute hepatic failure and targeting genetic markers to hepatic cells.Ledley FD Woo SL Ferry GD Whisennand HH Brandt ML Darlington GJ Demmler GJ Finegold MJ Pokorny WJ Rosenblatt H. Hum Gene Ther. 1991 Winter 2(4)331-58. Review Hepatocyte transplantation-biology and application. Ann Transplant. 2007 Review Hepatocyte transplantation-biology and application.Gewartowska M Olszewski WL. Ann Transplant. 2007 12(1)27-36. Historical aspects of hepatocyte transplantation. Transplant Proc. 2006 Historical aspects of hepatocyte transplantation.Bruzzone P Strom SC. Transplant Proc. 2006 May 38(4)1179-80. Review Hepatocyte transplantation clinical experience and potential for future use. Cell Transplant. 2006 Review Hepatocyte transplantation clinical experience and potential for future use.Strom SC Bruzzone P Cai H Ellis E Lehmann T Mitamura K Miki T. Cell Transplant. 2006 15 Suppl 1S105-10. Review New management options for end-stage chronic liver disease and acute liver failure potential for pediatric patients. Paediatr Drugs. 2006 Review New management options for end-stage chronic liver disease and acute liver failure potential for pediatric patients.Debray D Yousef N Durand P. Paediatr Drugs. 2006 8(1)1-13. See reviews... See all... Recent activity Clear Turn Off Turn On Hepatic cell transplantation a new therapy in liver diseases. Hepatic cell transplantation a new therapy in liver diseases.Cir Esp. 2010 Jul 88(1)3-11. Epub 2010 May 26 . PubMed Your browsing activity is empty. Activity recording is turned off. Turn recording back on See more... You are here NCBI gt Literature gt PubMed Write to the Help Desk Simple NCBI Directory Getting Started NCBI Education NCBI Help Manual NCBI Handbook Training amp Tutorials Resources Chemicals amp BioassaysData amp SoftwareDNA amp RNADomains amp StructuresGenes amp ExpressionGenetics amp MedicineGenomes amp MapsHomologyLiteratureProteinsSequence AnalysisTaxonomyTraining amp TutorialsVariation Popular PubMed Nucleotide BLAST PubMed Central Gene Bookshelf Protein OMIM Genome SNP Structure Featured GenBank Reference Sequences Map Viewer Genome Projects Human Genome Mouse Genome Influenza Virus Primer-BLAST Sequence Read Archive NCBI Information About NCBI Research at NCBI NCBI Newsletter NCBI FTP Site NCBI on Facebook NCBI on Twitter NCBI on YouTube NIH DHHS USA.gov Copyright | Disclaimer | Privacy | Accessibility | Contact National Center for Biotechnology Information U.S. National Library of Medicine 8600 Rockville Pike Bethesda MD 20894 USA
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