Abstract : In this study, the effects of
alternate use of imipenem and cefoperazone/
sulbactam(CFP/Sul) on
more
Abstract : In this study, the effects of
alternate use of imipenem and cefoperazone/
sulbactam(CFP/Sul) on
antibiotic resistance in the intensive
care unit (ICU) were investigated.
Between 1 April 1993 and 1 April
1994, the infectious diseases consultant
saw patients when required
and there was no alternative therapy
for antibiotics. For the following
2 years, the same consultant followed
up each patient from admission
to discharge by daily visits to
the ICU and an alternative therapy
protocol was initiated. The most
common microorganisms were
found to be Acinetobacter baumannii
and Staphylococcus aureus, followed
by Pseudomonas aeruginosa
and Klebsiella pneumoniae, respectively,
in the two periods. This study
demonstrated that sensitivity rates
of imipenem, ciprofloxacin and aminoglycosides
were improved as a
result of this protocol.
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