Abstract : Although clinical trials for new drugs are often limited in children because of safety concerns or
more
Abstract : Although clinical trials for new drugs are often limited in children because of safety concerns or restrictions new therapies or novel strategies with old drugs have recently expanded dermatologic armamentarium for pediatric patients. Oral propranolol is currently the first choice in the treatment of alarming infantile hemangiomas. In atopic dermatitis proactive strategy with topical calcineurin inhibitors can safely prevent disease exacerbation. Tacrolimus in particular is also useful for the treatment of vitiligo occurring in sensitive areas such as the eyelids. Among biologic drugs use of etanercept is safe and efficient in children and adolescents with moderate-to-severe plaque psoriasis. Engineered tissues with special antimicrobial properties (silver-coated fabrics or engineered silk) are now used to treat eczema and fungal diseases in children. In athletes foot the use of 5-finger socks can also be helpful.Copyright 2010 Elsevier Inc. All rights reserved.PMID 20510770 PubMed - indexed for MEDLINEMeSH Terms SubstancesMeSH TermsAdolescentAdrenal Cortex Hormones/geneticsAdrenal Cortex Hormones/therapeutic useAlopecia Areata/drug therapyAlopecia Areata/geneticsAutoimmune Diseases/drug therapyAutoimmune Diseases/geneticsChildChild PreschoolDermatitis Atopic/drug therapyDermatitis Atopic/geneticsEczema/drug therapyFemaleHemangioma/drug therapyHemangioma/geneticsHumansImmunosuppressive Agents/therapeutic useMalePropranolol/therapeutic usePsoriasis/drug therapyPsoriasis/geneticsRandomized Controlled Trials as TopicSkin Diseases/genetics*Skin Diseases/therapy*Tacrolimus/therapeutic useTherapies Investigational*Vitiligo/drug therapySubstancesAdrenal Cortex HormonesImmunosuppressive AgentsTacrolimusPropranololLinkOut - more resourcesFull Text SourcesElsevier ScienceW.B. SaundersMD ConsultOther Literature SourcesCOS Scholar UniverseMedicalSkin Conditions - MedlinePlus Health InformationMolecular Biology DatabasesPROPRANOLOL HYDROCHLORIDE - HSDB Supplemental Content Related citations Review Innovative use of topical calcineurin inhibitors. Dermatol Clin. 2010 Review Innovative use of topical calcineurin inhibitors.Lin AN. Dermatol Clin. 2010 Jul 28(3)535-45. Review Two topical calcineurin inhibitors for the treatment of atopic dermatitis in pediatric patients a meta-analysis of randomized clinical trials. J Dermatolog Treat. 2010 Review Two topical calcineurin inhibitors for the treatment of atopic dermatitis in pediatric patients a meta-analysis of randomized clinical trials.Chen SL Yan J Wang FS. J Dermatolog Treat. 2010 May 21(3)144-56. Review Whats new in pediatric dermatology?. Ann Dermatol Venereol. 2009 Review Whats new in pediatric dermatology?.Mazereeuw-Hautier J. Ann Dermatol Venereol. 2009 Dec 136 Suppl 7S426-35. Review Whats new in pediatric dermatology update for the pediatrician. Curr Opin Pediatr. 2004 Review Whats new in pediatric dermatology update for the pediatrician.Sidbury R. Curr Opin Pediatr. 2004 Aug 16(4)410-4. Therapy of atopic eczema with calcineurin inhibitors. J Dtsch Dermatol Ges. 2005 Therapy of atopic eczema with calcineurin inhibitors.Luger TA Bieber T Meurer M Mrowietz U Schwarz T Simon J Werfel T Zuberbier T. J Dtsch Dermatol Ges. 2005 May 3(5)385-91. See reviews... See all... All links from this record Related Citations Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant with the “linked from” citation displayed first. Compound (MeSH Keyword) PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles. Substance (MeSH Keyword) PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles. Recent activity Clear Turn Off Turn On Innovative therapeutics in pediatric dermatology. Innovative therapeutics in pediatric dermatology.Dermatol Clin. 2010 Jul 28(3)619-29. PubMed Your browsing activity is empty. Activity recording is turned off. Turn recording back on See more... You are here NCBI gt Literature gt PubMed Write to the Help Desk Simple NCBI Directory Getting Started NCBI Education NCBI Help Manual NCBI Handbook Training amp Tutorials Resources Chemicals amp BioassaysData amp SoftwareDNA amp RNADomains amp StructuresGenes amp ExpressionGenetics amp MedicineGenomes amp MapsHomologyLiteratureProteinsSequence AnalysisTaxonomyTraining amp TutorialsVariation Popular PubMed Nucleotide BLAST PubMed Central Gene Bookshelf Protein OMIM Genome SNP Structure Featured GenBank Reference Sequences Map Viewer Genome Projects Human Genome Mouse Genome Influenza Virus Primer-BLAST Sequence Read Archive NCBI Information About NCBI Research at NCBI NCBI Newsletter NCBI FTP Site NCBI on Facebook NCBI on Twitter NCBI on YouTube NIH DHHS USA.gov Copyright | Disclaimer | Privacy | Accessibility | Contact National Center for Biotechnology Information U.S. National Library of Medicine 8600 Rockville Pike Bethesda MD 20894 USA
less