Abstract : Metronidazole is a synthetic nitroimidazole derivative with antimicrobial and antiinflammatory prop
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Abstract : Metronidazole is a synthetic nitroimidazole derivative with antimicrobial and antiinflammatory properties. It was the first topical therapy approved solely for rosacea and remains a cornerstone of rosacea management. This article reviews the optimal use of topical metronidazole in the treatment of rosacea and other innovative but off-label dermatologic uses reported in the literature.Copyright 2010 Elsevier Inc. All rights reserved.PMID 20510762 PubMed - indexed for MEDLINEPublication Types MeSH Terms SubstancesPublication Types ReviewMeSH TermsAcute Generalized Exanthematous Pustulosis/drug therapyAdministration CutaneousAdultAnti-Infective Agents/administration amp dosageAnti-Infective Agents/adverse effectsAnti-Infective Agents/therapeutic use*Anti-Inflammatory Agents Non-Steroidal/administration amp dosageAnti-Inflammatory Agents Non-Steroidal/adverse effectsAnti-Inflammatory Agents Non-Steroidal/therapeutic use*ChildDermatitis Perioral/drug therapyDermatitis Seborrheic/drug therapyDouble-Blind MethodDrug Eruptions/diagnosisDrug Eruptions/etiologyFemaleHumansMaleMetronidazole/administration amp dosageMetronidazole/adverse effectsMetronidazole/therapeutic use*Multicenter Studies as TopicOff-Label UseRandomized Controlled Trials as TopicReceptor Epidermal Growth Factor/antagonists amp inhibitorsRosacea/drug therapy*Therapies Investigational*Wounds and Injuries/drug therapySubstancesAnti-Infective AgentsAnti-Inflammatory Agents Non-SteroidalMetronidazoleReceptor Epidermal Growth FactorLinkOut - more resourcesFull Text SourcesElsevier ScienceW.B. SaundersMD ConsultMedicalRosacea - MedlinePlus Health InformationMolecular Biology DatabasesMETRONIDAZOLE - HSDB Supplemental Content Related citations Combined effect of anti-inflammatory dose doxycycline (40-mg doxycycline usp monohydrate controlled-release capsules) and metronidazole topical gel 1 in the treatment of rosacea. J Drugs Dermatol. 2007 Combined effect of anti-inflammatory dose doxycycline (40-mg doxycycline usp monohydrate controlled-release capsules) and metronidazole topical gel 1 in the treatment of rosacea.Fowler JF Jr. J Drugs Dermatol. 2007 Jun 6(6)641-5. Review An update on the role of topical metronidazole in rosacea. Skin Therapy Lett. 2006 Review An update on the role of topical metronidazole in rosacea.Zip C. Skin Therapy Lett. 2006 Mar 11(2)1-4. Allergic contact dermatitis to topical metronidazole - 3 cases. Contact Dermatitis. 2007 Allergic contact dermatitis to topical metronidazole - 3 cases.Madsen JT Thormann J Kerre S Andersen KE Goossens A. Contact Dermatitis. 2007 Jun 56(6)364-6. Review The role of topical metronidazole in the treatment of rosacea. Cutis. 2004 Review The role of topical metronidazole in the treatment of rosacea.Wolf JE Jr. Cutis. 2004 Jan 73(1 Suppl)19-28. Review Use of topical metronidazole in moderate to severe rosacea. Adv Ther. 2003 Review Use of topical metronidazole in moderate to severe rosacea.Lowe NJ. Adv Ther. 2003 Jul-Aug 20(4)177-90. See reviews... See all... All links from this record Related Citations Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant with the “linked from” citation displayed first. Compound (MeSH Keyword) PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles. Substance (MeSH Keyword) PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles. Recent activity Clear Turn Off Turn On Innovative use of topical metronidazole. Innovative use of topical metronidazole.Dermatol Clin. 2010 Jul 28(3)525-34. PubMed Your browsing activity is empty. Activity recording is turned off. Turn recording back on See more... You are here NCBI gt Literature gt PubMed Write to the Help Desk Simple NCBI Directory Getting Started NCBI Education NCBI Help Manual NCBI Handbook Training amp Tutorials Resources Chemicals amp BioassaysData amp SoftwareDNA amp RNADomains amp StructuresGenes amp ExpressionGenetics amp MedicineGenomes amp MapsHomologyLiteratureProteinsSequence AnalysisTaxonomyTraining amp TutorialsVariation Popular PubMed Nucleotide BLAST PubMed Central Gene Bookshelf Protein OMIM Genome SNP Structure Featured GenBank Reference Sequences Map Viewer Genome Projects Human Genome Mouse Genome Influenza Virus Primer-BLAST Sequence Read Archive NCBI Information About NCBI Research at NCBI NCBI Newsletter NCBI FTP Site NCBI on Facebook NCBI on Twitter NCBI on YouTube NIH DHHS USA.gov Copyright | Disclaimer | Privacy | Accessibility | Contact National Center for Biotechnology Information U.S. National Library of Medicine 8600 Rockville Pike Bethesda MD 20894 USA
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