Abstract : Primary Helicobacter pylori eradication rate using triple therapy (a proton pump inhibitor PPI + am
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Abstract : Primary Helicobacter pylori eradication rate using triple therapy (a proton pump inhibitor PPI + amoxicillin AMPC + clarithromycin CAM over 7 days) is showing a declining trend. In this study we report recent eradication rates and have evaluated the usefulness of a pack preparation of three drugs. H. pylori eradication rate was 85.1 (57/67) in 2004 but then fell to 75.2 (79/105) in 2005 70.1 (68/97) in 2006 and 69.9 (58/83) in 2007. With the introduction of packs (lansoprazole LPZ 60 mg AMPC 1500 mg CAM 400 mg) the eradication rate recovered to 78.0 (110/141) in 2008. A comparative study in 2008 delineated that the eradication rate in the pack group (88.4 38/43) was significantly higher than that of the conventional group (73.5 72/98). These results suggest that packs of eradication medicine are useful in increasing eradication success.Copyright 2010 Prous Science S.A.U. or its licensors. All rights reserved.PMID 20508872 PubMed - indexed for MEDLINEMeSH Terms SubstancesMeSH Terms2-Pyridinylmethylsulfinylbenzimidazoles/administration amp dosage2-Pyridinylmethylsulfinylbenzimidazoles/therapeutic use*AdultAgedAmoxicillin/administration amp dosageAmoxicillin/therapeutic use*Anti-Bacterial Agents/administration amp dosageAnti-Bacterial Agents/therapeutic useAnti-Ulcer Agents/administration amp dosageAnti-Ulcer Agents/therapeutic useClarithromycin/administration amp dosageClarithromycin/therapeutic use*Drug Therapy CombinationFemaleHelicobacter Infections/drug therapy*Helicobacter Infections/microbiologyHelicobacter pylori/drug effectsHelicobacter pylori/isolation amp purificationHumansMaleMiddle AgedProton Pump Inhibitors/administration amp dosageProton Pump Inhibitors/therapeutic useRetrospective StudiesSubstances2-PyridinylmethylsulfinylbenzimidazolesAnti-Bacterial AgentsAnti-Ulcer AgentsProton Pump InhibitorslansoprazoleAmoxicillinClarithromycinLinkOut - more resourcesFull Text SourcesProus ScienceMolecular Biology DatabasesAMOXICILLIN - HSDB Supplemental Content Related citations Comparative study of Helicobacter pylori eradication rates of twice-versus four-times-daily amoxicillin administered with proton pump inhibitor and clarithromycin a randomized study. Helicobacter. 2008 Comparative study of Helicobacter pylori eradication rates of twice-versus four-times-daily amoxicillin administered with proton pump inhibitor and clarithromycin a randomized study.Kim SY Lee SW Jung SW Koo JS Yim HJ Park JJ Chun HJ Lee HS Choi JH Kim CD et al. Helicobacter. 2008 Aug 13(4)282-7. A multicenter double-blind study on triple therapy with lansoprazole amoxicillin and clarithromycin for eradication of Helicobacter pylori in Japanese peptic ulcer patients. Helicobacter. 2001 A multicenter double-blind study on triple therapy with lansoprazole amoxicillin and clarithromycin for eradication of Helicobacter pylori in Japanese peptic ulcer patients.Asaka M Sugiyama T Kato M Satoh K Kuwayama H Fukuda Y Fujioka T Takemoto T Kimura K Shimoyama T et al. Helicobacter. 2001 Sep 6(3)254-61. Lafutidine versus lansoprazole in combination with clarithromycin and amoxicillin for one versus two weeks for Helicobacter pylori eradication in Korea. Helicobacter. 2008 Lafutidine versus lansoprazole in combination with clarithromycin and amoxicillin for one versus two weeks for Helicobacter pylori eradication in Korea.Kim N Park SH Seo GS Lee SW Kim JW Lee KJ Shin WC Kim TN Park MI Park JJ et al. Helicobacter. 2008 Dec 13(6)542-9. Review Eradication effect of lansoprazole-based triple therapy against H. pylori. Nippon Rinsho. 2004 Review Eradication effect of lansoprazole-based triple therapy against H. pylori.Sugiyama T Asaka M. Nippon Rinsho. 2004 Mar 62(3)483-8. Review Systematic review and meta-analysis proton pump inhibitor vs. ranitidine bismuth citrate plus two antibiotics in Helicobacter pylori eradication. Helicobacter. 2005 Review Systematic review and meta-analysis proton pump inhibitor vs. ranitidine bismuth citrate plus two antibiotics in Helicobacter pylori eradication.Gisbert JP Gonzalez L Calvet X. Helicobacter. 2005 Jun 10(3)157-71. See reviews... See all... All links from this record Related Citations Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant with the “linked from” citation displayed first. Compound (MeSH Keyword) PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles. Substance (MeSH Keyword) PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles. Recent activity Clear Turn Off Turn On The effectiveness of packed therapy with three drugs in Helicobacter pylori erad... The effectiveness of packed therapy with three drugs in Helicobacter pylori eradication in Japan.Methods Find Exp Clin Pharmacol. 2010 May 32(4)243-6. PubMed Your browsing activity is empty. Activity recording is turned off. 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