Abstract : Vitamin D has gone through a renaissance with the association of vitamin D deficiency with a wide a
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Abstract : Vitamin D has gone through a renaissance with the association of vitamin D deficiency with a wide array of common diseases including breast colorectal and prostate cancers cardio-vascular disease autoimmune conditions and infections. Vitamin D analogs constitute a valuable group of compounds which can be used to regulate gene expression in functions as varied as calcium and phosphate homeostasis as well as cell growth regulation and cell differentiation of a wide spectrum of cell types. This review will discuss the full range of vitamin D compounds currently available some of their possible uses and potential mechanisms of action.Copyright 2010 Elsevier Inc. All rights reserved.PMID 20511062 PubMed - indexed for MEDLINEPublication Types MeSH Terms Substances Grant SupportPublication Types Research Support Non-U.S. GovtReviewMeSH TermsAnimalsFemaleHumansHyperparathyroidism Secondary/drug therapyMaleMiceNeoplasms/drug therapyPsoriasis/drug therapyRatsReceptors Calcitriol/antagonists amp inhibitors*Retinoid X Receptors/metabolismVitamin D/analogs amp derivatives*Vitamin D/metabolismVitamin D Deficiency/pathologyVitamin D-Binding Protein/metabolismSubstancesReceptors CalcitriolRetinoid X ReceptorsVitamin D-Binding ProteinVitamin DGrant SupportCanadian Institutes of Health Research/CanadaLinkOut - more resourcesFull Text SourcesElsevier ScienceW.B. SaundersMD ConsultMedicalVitamin D - MedlinePlus Health Information Supplemental Content Related citations Review Vitamin D analogs therapeutic applications and mechanisms for selectivity. Mol Aspects Med. 2008 Review Vitamin D analogs therapeutic applications and mechanisms for selectivity.Brown AJ Slatopolsky E. Mol Aspects Med. 2008 Dec 29(6)433-52. Epub 2008 May 1. Review Recent progress of study on vitamin D analogs. Clin Calcium. 2006 Review Recent progress of study on vitamin D analogs.Kittaka A Saito N Takano M. Clin Calcium. 2006 Jul 16(7)1154-65. Review Vitamin D analogs mechanism of action and therapeutic applications. Curr Med Chem. 2001 Review Vitamin D analogs mechanism of action and therapeutic applications.Nagpal S Lu J Boehm MF. Curr Med Chem. 2001 Nov 8(13)1661-79. Review Vitamin D analogs as therapeutic agents a clinical study update. Curr Opin Investig Drugs. 2004 Review Vitamin D analogs as therapeutic agents a clinical study update.Wu-Wong JR Tian J Goltzman D. Curr Opin Investig Drugs. 2004 Mar 5(3)320-6. Effect of 2-methylene-19-nor-(20S)-1 alpha-hydroxy-bishomopregnacalciferol (2MbisP) an analog of vitamin D on secondary hyperparathyroidism. J Bone Miner Res. 2007 Effect of 2-methylene-19-nor-(20S)-1 alpha-hydroxy-bishomopregnacalciferol (2MbisP) an analog of vitamin D on secondary hyperparathyroidism.Slatopolsky E Finch JL Brown AJ Ritter CS Mizobuchi M Plum LA Clagett-Dame M Sicinski RR DeLuca HF. J Bone Miner Res. 2007 May 22(5)686-94. See reviews... See all... All links from this record Related Citations Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant with the “linked from” citation displayed first. Substance (MeSH Keyword) PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles. Recent activity Clear Turn Off Turn On Vitamin D analogs. Vitamin D analogs.Endocrinol Metab Clin North Am. 2010 Jun 39(2)447-72 table of contents. PubMed Your browsing activity is empty. Activity recording is turned off. Turn recording back on See more... You are here NCBI gt Literature gt PubMed Write to the Help Desk Simple NCBI Directory Getting Started NCBI Education NCBI Help Manual NCBI Handbook Training amp Tutorials Resources Chemicals amp BioassaysData amp SoftwareDNA amp RNADomains amp StructuresGenes amp ExpressionGenetics amp MedicineGenomes amp MapsHomologyLiteratureProteinsSequence AnalysisTaxonomyTraining amp TutorialsVariation Popular PubMed Nucleotide BLAST PubMed Central Gene Bookshelf Protein OMIM Genome SNP Structure Featured GenBank Reference Sequences Map Viewer Genome Projects Human Genome Mouse Genome Influenza Virus Primer-BLAST Sequence Read Archive NCBI Information About NCBI Research at NCBI NCBI Newsletter NCBI FTP Site NCBI on Facebook NCBI on Twitter NCBI on YouTube NIH DHHS USA.gov Copyright | Disclaimer | Privacy | Accessibility | Contact National Center for Biotechnology Information U.S. National Library of Medicine 8600 Rockville Pike Bethesda MD 20894 USA
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